Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway
Summary: Adipose tissue inflammation is one pathway shown to mediate insulin resistance in obese humans and rodents. Obesity induces dynamic cellular changes in adipose tissue to increase proinflammatory cytokines and diminish anti-inflammatory cytokines. However, we have found that anti-inflammator...
Hauptverfasser: | , , , , , |
---|---|
Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
Elsevier
2014-12-01
|
Schriftenreihe: | Cell Reports |
Online Zugang: | http://www.sciencedirect.com/science/article/pii/S2211124714009371 |