Adipocyte-Specific IKKβ Signaling Suppresses Adipose Tissue Inflammation through an IL-13-Dependent Paracrine Feedback Pathway

Summary: Adipose tissue inflammation is one pathway shown to mediate insulin resistance in obese humans and rodents. Obesity induces dynamic cellular changes in adipose tissue to increase proinflammatory cytokines and diminish anti-inflammatory cytokines. However, we have found that anti-inflammator...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Hyokjoon Kwon, Sarnia Laurent, Yan Tang, Haihong Zong, Pratibha Vemulapalli, Jeffrey E. Pessin
Format: Artikel
Sprache:English
Veröffentlicht: Elsevier 2014-12-01
Schriftenreihe:Cell Reports
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2211124714009371