Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping.

Perm-seq: Mapping Protein-DNA Interactions in Segmental Duplication and Highly Repetitive Regions of Genomes with Prior-Enhanced Read Mapping.

Segmental duplications and other highly repetitive regions of genomes contribute significantly to cells' regulatory programs. Advancements in next generation sequencing enabled genome-wide profiling of protein-DNA interactions by chromatin immunoprecipitation followed by high throughput sequenc...

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Bibliographic Details
Main Authors: Xin Zeng, Bo Li, Rene Welch, Constanza Rojo, Ye Zheng, Colin N Dewey, Sündüz Keleş
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4618727?pdf=render

Internet

http://europepmc.org/articles/PMC4618727?pdf=render

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