Parsing altered gray matter morphology of depression using a framework integrating the normative model and non-negative matrix factorization

Abstract The high inter-individual heterogeneity in individuals with depression limits neuroimaging studies with case-control approaches to identify promising biomarkers for individualized clinical decision-making. We put forward a framework integrating the normative model and non-negative matrix fa...

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Bibliographic Details
Main Authors: Shaoqiang Han, Qian Cui, Ruiping Zheng, Shuying Li, Bingqian Zhou, Keke Fang, Wei Sheng, Baohong Wen, Liang Liu, Yarui Wei, Huafu Chen, Yuan Chen, Jingliang Cheng, Yong Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39861-z