Unbalanced IDO1/IDO2 Endothelial Expression and Skewed Keynurenine Pathway in the Pathogenesis of COVID-19 and Post-COVID-19 Pneumonia

Unbalanced IDO1/IDO2 Endothelial Expression and Skewed Keynurenine Pathway in the Pathogenesis of COVID-19 and Post-COVID-19 Pneumonia

Despite intense investigation, the pathogenesis of COVID-19 and the newly defined long COVID-19 syndrome are not fully understood. Increasing evidence has been provided of metabolic alterations characterizing this group of disorders, with particular relevance of an activated tryptophan/kynurenine pa...

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Bibliographic Details
Main Authors: Marco Chilosi, Claudio Doglioni, Claudia Ravaglia, Guido Martignoni, Gian Luca Salvagno, Giovanni Pizzolo, Vincenzo Bronte, Venerino Poletti
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biomedicines
Subjects:
COVID-19
IDO
post-acute COVID syndrome
PACS
SARS-CoV-2
tryptophan/kynurenine
Online Access:https://www.mdpi.com/2227-9059/10/6/1332

Internet

https://www.mdpi.com/2227-9059/10/6/1332

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