pH-Responsive Liposomes of Dioleoyl Phosphatidylethanolamine and Cholesteryl Hemisuccinate for the Enhanced Anticancer Efficacy of Cisplatin

pH-Responsive Liposomes of Dioleoyl Phosphatidylethanolamine and Cholesteryl Hemisuccinate for the Enhanced Anticancer Efficacy of Cisplatin

The current study aimed to develop pH-responsive cisplatin-loaded liposomes (CDDP@PLs) via the thin film hydration method. Formulations with varied ratios of dioleoyl phosphatidylethanolamine (DOPE) to cholesteryl hemisuccinate (CHEMS) were investigated to obtain the optimal particle size, zeta pote...

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Bibliographic Details
Main Authors: Hassan Shah, Asadullah Madni, Muhammad Muzamil Khan, Fiaz-ud-Din Ahmad, Nasrullah Jan, Safiullah Khan, Muhammad Abdur Rahim, Shahzeb Khan, Meser M. Ali, Mohsin Kazi
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
cisplatin
pH-responsive liposomes
MDA-MB-231 cell lines
SK-OV-3 cell lines
confocal scanning laser microscopy
Online Access:https://www.mdpi.com/1999-4923/14/1/129

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https://www.mdpi.com/1999-4923/14/1/129

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