T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest.

T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest.

Molecular pathways regulating rapid proliferation and persistence are fundamental for pathogens but are not elucidated fully in Toxoplasma gondii. Promoters of T. gondii ribosomal proteins (RPs) were analyzed by EMSAs and ChIP. One RP promoter domain, known to bind an Apetela 2, bound to nuclear ext...

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Bibliographic Details
Main Authors: Samuel L Hutson, Ernest Mui, Karen Kinsley, William H Witola, Michael S Behnke, Kamal El Bissati, Stephen P Muench, Brittany Rohrman, Susan R Liu, Robert Wollmann, Yuko Ogata, Ali Sarkeshik, John R Yates, Rima McLeod
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2989910?pdf=render

Internet

http://europepmc.org/articles/PMC2989910?pdf=render

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