Lipocalin-2: a therapeutic target to overcome neurodegenerative diseases by regulating reactive astrogliosis
Abstract Glial cell activation precedes neuronal cell death during brain aging and the progression of neurodegenerative diseases. Under neuroinflammatory stress conditions, lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin or 24p3, is produced and secreted by activated mic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-10-01
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Series: | Experimental and Molecular Medicine |
Online Access: | https://doi.org/10.1038/s12276-023-01098-7 |