Reclassifying tumour cell cycle activity in terms of its tissue of origin

Abstract Genomic alterations resulting in loss of control over the cell cycle is a fundamental hallmark of human malignancies. Whilst pan-cancer studies have broadly assessed tumour genomics and their impact on oncogenic pathways, analyses taking the baseline signalling levels in normal tissue into...

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Bibliographic Details
Main Authors: Arian Lundberg, Joan Jong Jing Yi, Linda S. Lindström, Nicholas P. Tobin
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00302-7