Reclassifying tumour cell cycle activity in terms of its tissue of origin
Abstract Genomic alterations resulting in loss of control over the cell cycle is a fundamental hallmark of human malignancies. Whilst pan-cancer studies have broadly assessed tumour genomics and their impact on oncogenic pathways, analyses taking the baseline signalling levels in normal tissue into...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-022-00302-7 |