Computational modeling of complex bioenergetic mechanisms that modulate CD4+ T cell effector and regulatory functions
Abstract We built a computational model of complex mechanisms at the intersection of immunity and metabolism that regulate CD4+ T cell effector and regulatory functions by using coupled ordinary differential equations. The model provides an improved understanding of how CD4+ T cells are shaping the...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | npj Systems Biology and Applications |
Online Access: | https://doi.org/10.1038/s41540-022-00263-4 |