Pathological complete response after neoadjuvant immunotherapy combined with chemotherapy in pediatric rectal carcinoma: A case report

Pathological complete response after neoadjuvant immunotherapy combined with chemotherapy in pediatric rectal carcinoma: A case report

BackgroundPediatric colorectal carcinoma (PCRC) is a rare non-embryonal tumor with an incidence of 0.1% to 1% of adults. Immune checkpoint inhibitors (ICIs) targeting programmed death-1 (PD-1) have shown significant efficacy in defective mismatch repair/Microsatellite instability-high (dMMR/MSI-H) m...

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Bibliographic Details
Main Authors: Xiaomeng Cao, Jianwei Luo, Baoyin Zhao, Hongjiang Fu, Wendi Kang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
pediatric colorectal cancer
pathological complete response
neoadjuvant immunotherapy
microsatellite instability-high
immune checkpoint inhibitors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036181/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1036181/full

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