Efficacy of psychotherapy versus pharmacotherapy, or their combination, in chronic depression: study protocol for a systematic review and network meta-analysis using aggregated and individual patient data

Introduction Chronic depression represents a common and highly disabling disorder. Several randomised controlled trials (RCTs) investigated the effectiveness of psychological, pharmacological and combined treatments for chronic depression. This is the first overarching systematic review and network...

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Main Authors: Toshi A Furukawa, Pim Cuijpers, Adriani Nikolakopoulou, Julia Müller, Elisabeth Schramm, Martin B Keller, Daniel N Klein, Moritz Elsaesser, Efthimiou Orestis, Nana-Adjoa Kwarteng, Theodoros Evrenoglou
Format: Article
Language:English
Published: BMJ Publishing Group 2025-02-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/2/e089356.full