Cyclocytidine hydrochloride inhibits the synthesis of relaxed circular DNA of hepatitis B virus

Background Cyclocytidine hydrochloride (HCl) has been reported to inhibit DNA synthesis by affecting DNA polymerase. Here, we tested the antiviral effect of cyclocytidine on hepatitis B virus (HBV) DNA synthesis, which is reliant on DNA polymerase activity. Materials and Methods Cyclocytidine HCl wa...

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Bibliographic Details
Main Authors: Xue Wang, Yihan Xiao, Zhigang Cui, Zongxin Li, Lihua Li, Lixian Wu, Feifei Yin, Xiuji Cui
Format: Article
Language:English
Published: PeerJ Inc. 2022-07-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/13719.pdf