Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site

Fecal Microbiota Transplantation Exerts Neuroprotective Effects in a Mouse Spinal Cord Injury Model by Modulating the Microenvironment at the Lesion Site

ABSTRACT The primary traumatic event that causes spinal cord injury (SCI) is followed by a progressive secondary injury featured by vascular disruption and ischemia, inflammatory responses and the release of cytotoxic debris, which collectively add to the hostile microenvironment of the lesioned cor...

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Bibliographic Details
Main Authors: Yingli Jing, Fan Bai, Limiao Wang, Degang Yang, Yitong Yan, Qiuying Wang, Yanbing Zhu, Yan Yu, Zhiguo Chen
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:Microbiology Spectrum
Subjects:
fecal microbiota transplantation
microenvironment
spinal cord injury
vascular repair
inflammation
β-alanine
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00177-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.00177-22

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