Syndecan-1 Is Overexpressed in Human Thoracic Aneurysm but Is Dispensable for the Disease Progression in a Mouse Model

Syndecan-1 Is Overexpressed in Human Thoracic Aneurysm but Is Dispensable for the Disease Progression in a Mouse Model

Glycosaminoglycans (GAGs) pooling has long been considered as one of the histopathological characteristics defining thoracic aortic aneurysm (TAA) together with smooth muscle cells (SMCs) apoptosis and elastin fibers degradation. However, little information is known about GAGs composition or their p...

Full description

Bibliographic Details
Main Authors: Sara Zalghout, Sophie Vo, Véronique Arocas, Soumaya Jadoui, Eva Hamade, Bassam Badran, Olivier Oudar, Nathalie Charnaux, Dan Longrois, Yacine Boulaftali, Marie-Christine Bouton, Benjamin Richard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Syndecan-1
aneurysm
proteoglycan
extracellular matrix
smooth muscle cell (SMC)
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.839743/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2022.839743/full

Similar Items