Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

Activation of arcuate nucleus glucagon-like peptide-1 receptor-expressing neurons suppresses food intake

Abstract Background Central nervous system (CNS) control of metabolism plays a pivotal role in maintaining energy balance. In the brain, Glucagon-like peptide 1 (GLP-1), encoded by the proglucagon ‘Gcg’ gene, produced in a distinct population of neurons in the nucleus tractus solitarius (NTS), has b...

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Bibliographic Details
Main Authors: Ishnoor Singh, Le Wang, Baijuan Xia, Ji Liu, Azeddine Tahiri, Abdelfattah El Ouaamari, Michael B. Wheeler, Zhiping P. Pang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cell & Bioscience
Subjects:
Glucagon-like peptide-1
Hypothalamus
Pro-opiomelanocortin
Exendin-4
Chemogenetics
Glucose tolerance
Online Access:https://doi.org/10.1186/s13578-022-00914-3

Internet

https://doi.org/10.1186/s13578-022-00914-3

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