The Biological and Clinical Significance of Glutaminase in Luminal Breast Cancer

The glutamine metabolism has a key role in the regulation of uncontrolled tumour growth. This study aimed to evaluate the expression and prognostic significance of glutaminase in luminal breast cancer (BC). The glutaminase isoforms (GLS/GLS2) were assessed at genomic/transcriptomic levels, using MET...

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Bibliographic Details
Main Authors: Brendah K. Masisi, Rokaya El Ansari, Lutfi Alfarsi, Madeleine L. Craze, Natasha Jewa, Andrew Oldfield, Hayley Cheung, Michael Toss, Emad A. Rakha, Andrew R. Green
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/16/3963