Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses

Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses

Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent and drug-resistant HSV infections. A series of amidinourea compounds, designed as analogues...

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Bibliographic Details
Main Authors: Anita Toscani, Rossana Denaro, Sergio Fernando Castillo Pacheco, Matteo Biolatti, Silvia Anselmi, Valentina Dell’Oste, Daniele Castagnolo
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Molecules
Subjects:
amidinourea
herpes simplex virus
guanidine
antivirals
amidines
Online Access:https://www.mdpi.com/1420-3049/26/16/4927

Internet

https://www.mdpi.com/1420-3049/26/16/4927

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