Transcriptomic Analysis of Mineralized Adipose-Derived Stem Cell Tissues for Calcific Valve Disease Modelling

Transcriptomic Analysis of Mineralized Adipose-Derived Stem Cell Tissues for Calcific Valve Disease Modelling

Calcific aortic valve disease (CAVD) is characterized by the fibrosis and mineralization of the aortic valve, which leads to aortic stenosis and heart failure. At the cellular level, this is due to the osteoblastic-like differentiation of valve interstitial cells (VICs), resulting in the calcificati...

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Bibliographic Details
Main Authors: Alyssa Brodeur, Vincent Roy, Lydia Touzel-Deschênes, Stéphanie Bianco, Arnaud Droit, Julie Fradette, Jean Ruel, François Gros-Louis
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
tissue engineering
adipose-derived stromal/stem cells
RNA sequencing
calcific aortic valve disease
disease modelling
extracellular matrix
Online Access:https://www.mdpi.com/1422-0067/25/4/2291

Internet

https://www.mdpi.com/1422-0067/25/4/2291

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