Regulation of Macrophage, Dendritic Cell and Microglial Phenotype and Function by the SOCS proteins

Macrophages are innate immune cells of dynamic phenotype that rapidly respond to external stimuli in the microenvironment by altering their phenotype to respond to and to direct the immune response. The ability to dynamically change phenotype must be carefully regulated to prevent uncontrolled infla...

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Bibliographic Details
Main Authors: Sarah Michelle McCormick, Nicola M Heller
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00549/full