Stimulation of Oxytocin Receptor during Early Reperfusion Period Protects the Heart against Ischemia/Reperfusion Injury: the Role of Mitochondrial ATPSensitive Potassium Channel, Nitric Oxide, and Prostaglandins

Stimulation of Oxytocin Receptor during Early Reperfusion Period Protects the Heart against Ischemia/Reperfusion Injury: the Role of Mitochondrial ATPSensitive Potassium Channel, Nitric Oxide, and Prostaglandins

Postconditioning is a simple and safe strategy for cardioprotection and infarct size limitation. Our previous study showed that oxytocin (OT) exerts postconditioning effect on ischemic/reperfused isolated rat heart. The aim of this study was to investigate the involvement of OT receptor, mitochondri...

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Bibliographic Details
Main Authors: Alireza Imani, Maryam Khansari, Yaser Azizi, Kamran Rakhshan, Mahdieh Faghihi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-10-01
Series:Acta Medica Iranica
Subjects:
Oxytocin
Postconditioning
mKATP
NO
Cyclooxygenase
Isolated heart
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/4275

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/4275

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