Cyclophilin A causes severe fever with thrombocytopenia syndrome virus-induced cytokine storm by regulating mitogen-activated protein kinase pathway

Cyclophilin A causes severe fever with thrombocytopenia syndrome virus-induced cytokine storm by regulating mitogen-activated protein kinase pathway

IntroductionSevere fever with thrombocytopenia syndrome (SFTS) has become a global threat to public health since its first report in China in 2009. However, the pathogenesis of SFTS virus (SFTSV) in humans remains unclear. Also, there are no effective therapeutics for SFTS. Cyclophilin A (CyPA) regu...

Full description

Bibliographic Details
Main Authors: Huaying Huang, Ke Jin, Ke Ouyang, Zhengyi Jiang, Zhan Yang, Nannan Hu, Yan Dai, Yaqin Zhang, Qian Zhang, Ying Han, Jie Zhao, Hong Lin, Chunhui Wang, Chunyan Wang, Xuewei Sun, Dafeng Lu, Jin Zhu, Jun Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
severe fever with thrombocytopenia syndrome
Cyclophilin A
Cyclosporine A
mitogen-activated protein kinase
infection
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1046176/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1046176/full

Similar Items