Parental histone distribution and location of the replication obstacle at nascent strands control homologous recombination

Summary: The advance and stability of replication forks rely on a tight co-regulation of DNA synthesis and nucleosome assembly. We show that mutants affected in parental histone recycling are impaired in the recombinational repair of the single-stranded DNA gaps generated in response to DNA adducts...

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Bibliographic Details
Main Authors: Cristina González-Garrido, Félix Prado
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723001857