Long-Term High-Fat Diet Consumption Induces Cognitive Decline Accompanied by Tau Hyper-Phosphorylation and Microglial Activation in Aging

High-fat diet (HFD) intake is commonly related to a substantial risk of cognitive impairment for senior citizens over 65 years of age, which constitutes a profound global health burden with several economic and social consequences. It is critical to investigate the effects of long-term HFD consumpti...

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Bibliographic Details
Main Authors: Zheng Liang, Xiaokang Gong, Runjia Ye, Yang Zhao, Jin Yu, Yanna Zhao, Jian Bao
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/15/1/250