A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing

A Multifunctional and Highly Adaptable Reporter System for CRISPR/Cas Editing

CRISPR/Cas systems are some of the most promising tools for therapeutic genome editing. The use of these systems is contingent on the optimal designs of guides and homology-directed repair (HDR) templates. While this design can be achieved in silico, validation and further optimization are usually p...

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Bibliographic Details
Main Authors: Jochen M. Wettengel, Lea Hansen-Palmus, Sofiya Yusova, Lauren Rust, Sreya Biswas, Julien Carson, Junghyun Ryu, Benjamin N. Bimber, Jon D. Hennebold, Benjamin J. Burwitz
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
CRISPR-Cas reporter system
Cas9 activity
saCas9
spCas9
asCas12a
HDR
Online Access:https://www.mdpi.com/1422-0067/24/9/8271

Internet

https://www.mdpi.com/1422-0067/24/9/8271

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