Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma

Evaluation of the Interplay between the ADAR Editome and Immunotherapy in Melanoma

Background: RNA editing is a highly conserved posttranscriptional mechanism that contributes to transcriptome diversity. In mammals, it includes nucleobase deaminations that convert cytidine (C) into uridine (U) and adenosine (A) into inosine (I). Evidence from cancer studies indicates that RNA-edit...

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Bibliographic Details
Main Authors: Marina Tusup, Phil F. Cheng, Ernesto Picardi, Austeja Raziunaite, Reinhard Dummer, Mitchell P. Levesque, Lars E. French, Emmanuella Guenova, Thomas M. Kundig, Steve Pascolo
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Non-Coding RNA
Subjects:
editing
melanoma
ADAR
Alu sequences
immune checkpoint inhibitors
immunotherapy
Online Access:https://www.mdpi.com/2311-553X/7/1/5

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https://www.mdpi.com/2311-553X/7/1/5

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