Genetically Encoded Fluorescent Probe for Detection of Heme-Induced Conformational Changes in Cytochrome c
Cytochrome c (Cytc) is a key redox protein for energy metabolism and apoptosis in cells. The activation of Cytc is composed of several steps, including its transfer to the mitochondrial membrane, binding to cytochrome c heme lyase (CCHL) and covalent attachment to heme. The spectroscopic methods are...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-09-01
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Series: | Biosensors |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6374/13/9/890 |