Genetically Encoded Fluorescent Probe for Detection of Heme-Induced Conformational Changes in Cytochrome c

Genetically Encoded Fluorescent Probe for Detection of Heme-Induced Conformational Changes in Cytochrome c

Cytochrome c (Cytc) is a key redox protein for energy metabolism and apoptosis in cells. The activation of Cytc is composed of several steps, including its transfer to the mitochondrial membrane, binding to cytochrome c heme lyase (CCHL) and covalent attachment to heme. The spectroscopic methods are...

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Bibliographic Details
Main Authors: Mehmet Yunus Genceroglu, Cansu Cavdar, Selen Manioglu, Halil Bayraktar
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Biosensors
Subjects:
cytochrome c
cytochrome c heme lyase
heme
FRET
fluorescence
protein folding
Online Access:https://www.mdpi.com/2079-6374/13/9/890

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