Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults

Abstract Elevated blood pressure (BP) is major risk factor for cardiovascular diseases (CVD). Genome-wide association studies (GWAS) conducted predominantly in populations of European ancestry have identified >2,000 BP-associated loci, but other ancestries have been less well-studied. We conducte...

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Bibliographic Details
Main Authors: Alfred Pozarickij, Wei Gan, Kuang Lin, Robert Clarke, Zammy Fairhurst-Hunter, Masaru Koido, Masahiro Kanai, Yukinori Okada, Yoichiro Kamatani, Derrick Bennett, Huaidong Du, Yiping Chen, Ling Yang, Daniel Avery, Yu Guo, Min Yu, Canqing Yu, Dan Schmidt Valle, Jun Lv, Junshi Chen, Richard Peto, Rory Collins, Liming Li, Zhengming Chen, Iona Y. Millwood, Robin G. Walters, China Kadoorie Biobank Collaborative Group
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50297-x

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https://doi.org/10.1038/s41467-024-50297-x

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