A Simplified Iohexol-Based Method to Measure Renal Function in Sheep Models of Renal Disease

A Simplified Iohexol-Based Method to Measure Renal Function in Sheep Models of Renal Disease

Sheep are highly adequate models for human renal diseases because of their many similarities in the histology and physiology of kidney and pathogenesis of kidney diseases. However, the lack of a simple method to measure glomerular filtration rate (GFR) limits its use as a model of renal diseases. He...

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Bibliographic Details
Main Authors: Sergio Luis-Lima, Carolina Mas-Sanmartin, Ana Elena Rodríguez-Rodríguez, Esteban Porrini, Alberto Ortiz, Flavio Gaspari, Laura Diaz-Martin, Anders Åsberg, Trond Jenssen, Alejandro Jiménez-Sosa, Paula Martinez-Ros, Antonio Gonzalez-Bulnes
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biology
Subjects:
renal function
iohexol plasma clearance
sheep model
Online Access:https://www.mdpi.com/2079-7737/9/9/259

Internet

https://www.mdpi.com/2079-7737/9/9/259

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