WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines

WDR5 facilitates recruitment of N-MYC to conserved WDR5 gene targets in neuroblastoma cell lines

Abstract Collectively, the MYC family of oncoprotein transcription factors is overexpressed in more than half of all malignancies. The ability of MYC proteins to access chromatin is fundamental to their role in promoting oncogenic gene expression programs in cancer and this function depends on MYC–c...

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Bibliographic Details
Main Authors: Leigh A. Bumpous, Kylie C. Moe, Jing Wang, Logan A. Carver, Alexandria G. Williams, Alexander S. Romer, Jesse D. Scobee, Jack N. Maxwell, Cheyenne A. Jones, Dai H. Chung, William P. Tansey, Qi Liu, April M. Weissmiller
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-023-00477-z

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https://doi.org/10.1038/s41389-023-00477-z

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