Development of an LCâMS/MS method for determination of 2-oxo-clopidogrel in human plasma
A sensitive and selective liquid chromatographyâtandem mass spectrometric (LCâMS/MS) method was established to determine 2-oxo-clopidogrel, a crucial intermediate metabolite in human plasma. A chromatographic separation was performed on a Sapphire C18 column following a liquidâliquid extraction samp...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-02-01
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Series: | Journal of Pharmaceutical Analysis |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2095177914000641 |