Semisolid Wet Sol–Gel Silica/Hydroxypropyl Methyl Cellulose Formulation for Slow Release of Serpin B3 Promotes Wound Healing In Vivo

Semisolid Wet Sol–Gel Silica/Hydroxypropyl Methyl Cellulose Formulation for Slow Release of Serpin B3 Promotes Wound Healing In Vivo

Foot ulcerations are a disabling complication of diabetes and no treatment is currently available based on disease mechanisms. The protein serpin B3 (SB3) was identified as a positive biomarker of successful diabetic wound healing; therefore, its exogenous administration may promote healing. The top...

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Bibliographic Details
Main Authors: Mattia Albiero, Alice Fullin, Gianmarco Villano, Alessandra Biasiolo, Santina Quarta, Simone Bernardotto, Cristian Turato, Mariagrazia Ruvoletto, Gian Paolo Fadini, Patrizia Pontisso, Margherita Morpurgo
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
sol–gel silica
protein formulation
semisolid formulations
serpin B3
diabetic ulcer
chronic ulcer
Online Access:https://www.mdpi.com/1999-4923/14/9/1944

Internet

https://www.mdpi.com/1999-4923/14/9/1944

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