Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound
The deodorant activity of black cumin (<i>Nigella sativa</i> L.) seed, a spice used to flavor curry and vegetable foods in Southwest Asia, against garlic (<i>Allium sativum</i> L.) organosulfur compounds related to human malodor was evaluated. Black cumin seed essential oil s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/11/12/1874 |
| _version_ | 1827673954267955200 |
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| author | Yuri Yoshioka Shinichi Matsumura Masanori Morimoto |
| author_facet | Yuri Yoshioka Shinichi Matsumura Masanori Morimoto |
| author_sort | Yuri Yoshioka |
| collection | DOAJ |
| description | The deodorant activity of black cumin (<i>Nigella sativa</i> L.) seed, a spice used to flavor curry and vegetable foods in Southwest Asia, against garlic (<i>Allium sativum</i> L.) organosulfur compounds related to human malodor was evaluated. Black cumin seed essential oil showed remarkable deodorant activity against garlic essential oil. The mode of action of this deodorant activity was presumed to be that black cumin seed essential oil covalently reacted with the organosulfur compounds in garlic. Therefore, thymoquinone, which is a major constituent in black cumin seed essential oil, and allyl mercaptan, which is one of the organosulfur compounds produced by cutting garlic, were reacted in vitro, and the products were purified and elucidated using spectroscopic data. As a result, these substances were identified as different allyl mercaptan adducts to dihydrothymoquinone. This chemical reaction was presumed to play a key role in the deodorant activity of black cumin seed essential oil. |
| first_indexed | 2024-03-10T04:32:57Z |
| format | Article |
| id | doaj.art-978245fc22494634aa433ba8f1af6b6e |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-10T04:32:57Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-978245fc22494634aa433ba8f1af6b6e2023-11-23T04:00:31ZengMDPI AGBiomolecules2218-273X2021-12-011112187410.3390/biom11121874Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur CompoundYuri Yoshioka0Shinichi Matsumura1Masanori Morimoto2Natural Products, Inabata Koryo Co., Ltd., Yodogawa, Osaka 532-0027, JapanNatural Products, Inabata Koryo Co., Ltd., Yodogawa, Osaka 532-0027, JapanDepartment of Applied Biological Chemistry, School of Agriculture, Kindai University, Nara 631-8505, JapanThe deodorant activity of black cumin (<i>Nigella sativa</i> L.) seed, a spice used to flavor curry and vegetable foods in Southwest Asia, against garlic (<i>Allium sativum</i> L.) organosulfur compounds related to human malodor was evaluated. Black cumin seed essential oil showed remarkable deodorant activity against garlic essential oil. The mode of action of this deodorant activity was presumed to be that black cumin seed essential oil covalently reacted with the organosulfur compounds in garlic. Therefore, thymoquinone, which is a major constituent in black cumin seed essential oil, and allyl mercaptan, which is one of the organosulfur compounds produced by cutting garlic, were reacted in vitro, and the products were purified and elucidated using spectroscopic data. As a result, these substances were identified as different allyl mercaptan adducts to dihydrothymoquinone. This chemical reaction was presumed to play a key role in the deodorant activity of black cumin seed essential oil.https://www.mdpi.com/2218-273X/11/12/1874black cumin seed essential oildeodorant activitygarlic organosulfur compounds<i>Nigella sativa</i> L. |
| spellingShingle | Yuri Yoshioka Shinichi Matsumura Masanori Morimoto Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound Biomolecules black cumin seed essential oil deodorant activity garlic organosulfur compounds <i>Nigella sativa</i> L. |
| title | Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound |
| title_full | Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound |
| title_fullStr | Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound |
| title_full_unstemmed | Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound |
| title_short | Deodorant Activity of Black Cumin Seed Essential Oil against Garlic Organosulfur Compound |
| title_sort | deodorant activity of black cumin seed essential oil against garlic organosulfur compound |
| topic | black cumin seed essential oil deodorant activity garlic organosulfur compounds <i>Nigella sativa</i> L. |
| url | https://www.mdpi.com/2218-273X/11/12/1874 |
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