Sensitivity of Allelic Divergence to Genomic Position: Lessons from the Drosophila tan Gene

Sensitivity of Allelic Divergence to Genomic Position: Lessons from the Drosophila tan Gene

To identify genetic variants underlying changes in phenotypes within and between species, researchers often utilize transgenic animals to compare the function of alleles in different genetic backgrounds. In Drosophila, targeted integration mediated by the ΦC31 integrase allows activity of alternativ...

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Bibliographic Details
Main Authors: Alisha V. John, Lisa L. Sramkoski, Elizabeth A. Walker, Arielle M. Cooley, Patricia J. Wittkopp
Format: Article
Language:English
Published: Oxford University Press 2016-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
allele-specific
transgenic analysis
position effect
pigmentation
tan
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.032029

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.032029

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