The Combined Inactivation of Intestinal and Hepatic ZIP14 Exacerbates Manganese Overload in Mice

ZIP14 is a newly identified manganese transporter with high levels of expression in the small intestine and the liver. Loss-of-function mutations in <i>ZIP14</i> can lead to systemic manganese overload, which primarily affects the central nervous system, causing neurological disorders. T...

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Bibliographic Details
Main Authors: Caitlin K. Fung, Ningning Zhao
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/12/6495