The Combined Inactivation of Intestinal and Hepatic ZIP14 Exacerbates Manganese Overload in Mice
ZIP14 is a newly identified manganese transporter with high levels of expression in the small intestine and the liver. Loss-of-function mutations in <i>ZIP14</i> can lead to systemic manganese overload, which primarily affects the central nervous system, causing neurological disorders. T...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-06-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/12/6495 |