In vitro selection of Neisseria gonorrhoeae unveils novel mutations associated with extended-spectrum cephalosporin resistance

In vitro selection of Neisseria gonorrhoeae unveils novel mutations associated with extended-spectrum cephalosporin resistance

The emergence of Neisseria gonorrhoeae strains resistant to extended-spectrum cephalosporins (ESCs) is a worldwide concern because this class of antibiotics represents the last empirical treatment option for gonorrhea. The abusive use of antimicrobials may be an essential factor for the emergence of...

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Bibliographic Details
Main Authors: Marcos André Schörner, Dany Mesa, Fernando Hartmann Barazzetti, Jéssica Motta Martins, Hanalydia de Melo Machado, Henrique Borges da Silva Grisard, Julia Kinetz Wachter, Márick Rodrigues Starick, Mara Cristina Scheffer, Jussara Kasuko Palmeiro, Maria Luiza Bazzo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
SNP
whole-genome sequencing
PBP2
penA
resistance induction
mutations
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.924764/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.924764/full

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