Early Onset Ataxia with Comorbid Dystonia: Clinical, Anatomical and Biological Pathway Analysis Expose Shared Pathophysiology

Early Onset Ataxia with Comorbid Dystonia: Clinical, Anatomical and Biological Pathway Analysis Expose Shared Pathophysiology

In degenerative adult onset ataxia (AOA), dystonic comorbidity is attributed to one disease continuum. However, in early adult onset ataxia (EOA), the prevalence and pathogenesis of dystonic comorbidity (EOAD<sup>+</sup>), are still unclear. In 80 EOA-patients, we determined the EOAD<...

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Bibliographic Details
Main Authors: Deborah A. Sival, Martinica Garofalo, Rick Brandsma, Tom A. Bokkers, Marloes van den Berg, Tom J. de Koning, Marina A. J. Tijssen, Dineke S. Verbeek
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Diagnostics
Subjects:
clinical genetics
early onset ataxia
dystonia
neurodevelopment
network analysis
bioinformatics
Online Access:https://www.mdpi.com/2075-4418/10/12/997

Internet

https://www.mdpi.com/2075-4418/10/12/997

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