17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression

17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression

Abstract Background In non-small cell lung cancer (NSCLC), estrogen (E2) significantly promotes NSCLC cell growth via estrogen receptor beta (ERβ). Discovery and elucidation of the mechanism underlying estrogen-promoted NSCLC progression is critical for effective preventive interventions. IL6 has be...

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Bibliographic Details
Main Authors: Quanfu Huang, Zheng Zhang, Yongde Liao, Changyu Liu, Sheng Fan, Xiao Wei, Bo Ai, Jing Xiong
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
17β-estradiol
Estrogen receptor β
Interleukin 6
Non-small cell lung cancer
Online Access:http://link.springer.com/article/10.1186/s13046-018-0804-5

Internet

http://link.springer.com/article/10.1186/s13046-018-0804-5

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