Somatic point mutations are enriched in non-coding RNAs with possible regulatory function in breast cancer

The SomaGene tool is developed to identify non-coding RNAs (ncRNAs) mutated in breast cancer but can be used for other cancers. Candidate ncRNAs are shown to be enriched for regulatory features and to contain specific trait loci polymorphisms.

Bibliographic Details
Main Authors: Narges Rezaie, Masroor Bayati, Mehrab Hamidi, Maedeh Sadat Tahaei, Sadegh Khorasani, Nigel H. Lovell, James Breen, Hamid R. Rabiee, Hamid Alinejad-Rokny
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03528-0