p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model

Abstract Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of hyperphosphorylated tau protein in the brain. Many of these pathologies also present an inflammatory component determined by the activation of microglia, the resident immune cells of the brain. p38 MA...

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Bibliographic Details
Main Authors: Juan R. Perea, Esther García, Laura Vallés-Saiz, Raquel Cuadros, Félix Hernández, Marta Bolós, Jesús Avila
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-05980-8