p38 activation occurs mainly in microglia in the P301S Tauopathy mouse model
Abstract Tauopathies are a group of neurodegenerative diseases characterized by the accumulation of hyperphosphorylated tau protein in the brain. Many of these pathologies also present an inflammatory component determined by the activation of microglia, the resident immune cells of the brain. p38 MA...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-02-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-05980-8 |