CD4+ T cell mitochondrial genotype in Multiple Sclerosis: a cross-sectional and longitudinal analysis

Abstract Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS), with a largely unknown etiology, where mitochondrial dysfunction likely contributes to neuroaxonal loss and brain atrophy. Mirroring the CNS, peripheral immune cells from patients with...

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Bibliographic Details
Main Authors: Filipe Cortes-Figueiredo, Susanna Asseyer, Claudia Chien, Hanna G. Zimmermann, Klemens Ruprecht, Tanja Schmitz-Hübsch, Judith Bellmann-Strobl, Friedemann Paul, Vanessa A. Morais
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-57592-z