Black pepper (Piper nigrum L.) essential oil counteracts dexamethasone-induced hepatic injury via modulating PGC-1α/ PPAR-α pathway in rats

Black pepper (Piper nigrum L.) essential oil counteracts dexamethasone-induced hepatic injury via modulating PGC-1α/ PPAR-α pathway in rats

We previously characterized the volatile compounds of black pepper (Piper nigrum) essential oil (BPEO) and demonstrated its mitigating effect against dexamethasone-induced pancreatic damage. Herein, we investigated the protective effect of the oil against dexamethasone-induced hepatotoxicity in rats...

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Bibliographic Details
Main Authors: Mona F. Mahmoud, Ismail Mahdi, Noura Ali, Hanna Dib, Assem M. El-Shazly, Islam Mostafa, Mohamed A.O. Abdelfattah, Rehab A. Hasan, Mansour Sobeh
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Arabian Journal of Chemistry
Subjects:
Black pepper essential oil
Dexamethasone
Liver injury
Oxidative stress
PGC-1α/PPAR-α pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535224000923

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http://www.sciencedirect.com/science/article/pii/S1878535224000923

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