Top-Down Proteomics of Human Saliva Highlights Anti-inflammatory, Antioxidant, and Antimicrobial Defense Responses in Alzheimer Disease

Top-Down Proteomics of Human Saliva Highlights Anti-inflammatory, Antioxidant, and Antimicrobial Defense Responses in Alzheimer Disease

Alzheimer disease (AD) is the most prevalent neurodegenerative disease in the elderly, characterized by accumulation in the brain of misfolded proteins, inflammation, and oxidative damage leading to neuronal cell death. By considering the viewpoint that AD onset and worsening may be influenced by en...

Full description

Bibliographic Details
Main Authors: Cristina Contini, Alessandra Olianas, Simone Serrao, Carla Deriu, Federica Iavarone, Mozhgan Boroumand, Alessandra Bizzarro, Alessandra Lauria, Gavino Faa, Massimo Castagnola, Irene Messana, Barbara Manconi, Carlo Masullo, Tiziana Cabras
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer disease
salivary proteomics
S100A
cystatins
α-defensins
thymosin β4
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.668852/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.668852/full

Similar Items