Circularized Nanodiscs for Multivalent Mosaic Display of SARS-CoV-2 Spike Protein Antigens

Circularized Nanodiscs for Multivalent Mosaic Display of SARS-CoV-2 Spike Protein Antigens

The emergence of vaccine-evading SARS-CoV-2 variants urges the need for vaccines that elicit broadly neutralizing antibodies (bnAbs). Here, we assess covalently circularized nanodiscs decorated with recombinant SARS-CoV-2 spike glycoproteins from several variants for eliciting bnAbs with vaccination...

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Bibliographic Details
Main Authors: Moustafa T. Mabrouk, Asmaa A. Zidan, Nihal Aly, Mostafa T. Mohammed, Fadi Ghantous, Michael S. Seaman, Jonathan F. Lovell, Mahmoud L. Nasr
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Vaccines
Subjects:
nanodisc
vaccine
COVID-19
Online Access:https://www.mdpi.com/2076-393X/11/11/1655

Internet

https://www.mdpi.com/2076-393X/11/11/1655

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