C-Reactive Protein (CRP) Blocks the Desensitization of Agonistic Stimulated G Protein Coupled Receptors (GPCRs) in Neonatal Rat Cardiomyocytes

C-Reactive Protein (CRP) Blocks the Desensitization of Agonistic Stimulated G Protein Coupled Receptors (GPCRs) in Neonatal Rat Cardiomyocytes

Recently, C-reactive protein (CRP) was shown to affect intracellular calcium signaling and blood pressure in vitro and in vivo, respectively. The aim of the present study was to further investigate if a direct effect on G-protein coupled receptor (GPCR) signaling by CRP can be observed by using CRP...

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Bibliographic Details
Main Authors: Gerd Wallukat, Stephan Mattecka, Katrin Wenzel, Wieland Schrödl, Birgit Vogt, Patrizia Brunner, Ahmed Sheriff, Rudolf Kunze
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Journal of Clinical Medicine
Subjects:
C-reactive protein
adrenergic receptor
desensitization
GPCR signaling
endothelin
Online Access:https://www.mdpi.com/2077-0383/11/4/1058

Internet

https://www.mdpi.com/2077-0383/11/4/1058

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