Modeling Structures and Motions of Loops in Protein Molecules

Unlike the secondary structure elements that connect in protein structures, loop fragments in protein chains are often highly mobile even in generally stable proteins. The structural variability of loops is often at the center of a protein’s stability, folding, and even biological function. Loops ar...

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Bibliographic Details
Main Authors: Lydia E. Kavraki, Amarda Shehu
Format: Article
Language:English
Published: MDPI AG 2012-02-01
Series:Entropy
Subjects:
Online Access:http://www.mdpi.com/1099-4300/14/2/252/