The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B

The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B

The chemokine receptor CXCR3 plays a critical role in immune cell recruitment and activation. CXCR3 exists as two main isoforms, CXCR3-A and CXCR3-B, resulting from alternative splicing. Although the two isoforms differ only by the presence of an N-terminal extension in CXCR3-B, they have been attri...

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Bibliographic Details
Main Authors: Giulia D’Uonnolo, Nathan Reynders, Max Meyrath, Dayana Abboud, Tomasz Uchański, Toon Laeremans, Brian F. Volkman, Bassam Janji, Julien Hanson, Martyna Szpakowska, Andy Chevigné
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
ACKR3
ACKR2
CXCR3B
CXCL11/I-TAC
CXCL10/IP-10
arrestin
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.868579/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.868579/full

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