A short‐chain carbonyl reductase mutant is an efficient catalyst in the production of (R)‐1,3‐butanediol

Abstract R‐1,3‐butanediol (R‐1,3‐BDO) is an important chiral intermediate of penem and carbapenem synthesis. Among the different synthesis methods to obtain pure enantiomer R‐1,3‐BDO, oxidation–reduction cascades catalysed by enzymes are promising strategies for its production. Dehydrogenases have b...

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Bibliographic Details
Main Authors: Xiaoyan Guo, Yunfang Gao, Fangzheng Liu, Yong Tao, Haibo Jin, Jianjun Wang, Sheng Wu
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Microbial Biotechnology
Online Access:https://doi.org/10.1111/1751-7915.14249