Chitosan-alginate microcapsules of amoxicillin for gastric stability and mucoadhesion

Amoxicillin-loaded microcapsules were prepared by ionotropic gelation of sodium alginate (ALG) with chitosan (CS) in presence of calcium chloride as gastroretentive delivery system. The effect of pH, concentration of ALG, CS and calcium chloride, and drug : ALG ratio were optimized in this study for...

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Bibliographic Details
Main Authors: Saahil Arora, R D Budhiraja
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2012;volume=3;issue=1;spage=68;epage=74;aulast=Arora