Chitosan-alginate microcapsules of amoxicillin for gastric stability and mucoadhesion
Amoxicillin-loaded microcapsules were prepared by ionotropic gelation of sodium alginate (ALG) with chitosan (CS) in presence of calcium chloride as gastroretentive delivery system. The effect of pH, concentration of ALG, CS and calcium chloride, and drug : ALG ratio were optimized in this study for...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2012-01-01
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Series: | Journal of Advanced Pharmaceutical Technology & Research |
Subjects: | |
Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2012;volume=3;issue=1;spage=68;epage=74;aulast=Arora |