Human amniotic epithelial cells exert anti-cancer effects through secretion of immunomodulatory small extracellular vesicles (sEV)

Human amniotic epithelial cells exert anti-cancer effects through secretion of immunomodulatory small extracellular vesicles (sEV)

Highlights Anti-cancer effects of hAEC depend on cancer type. Cross-reactive humoral responses do not mediate anti-cancer effects of hAEC. Anti-cancer effects of hAECs are mainly mediated by small-extracellular vesicles (sEV). hAEC-derived sEV (AD-sEV) trigger the Warburg’s effect leading to Arginin...

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Bibliographic Details
Main Authors: Mohammad-Reza Bolouri, Roya Ghods, Kayhan Zarnani, Sedigheh Vafaei, Reza Falak, Amir-Hassan Zarnani
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Cancer Cell International
Subjects:
Stem cells
Human amniotic epithelial cell
Cancer
Small extracellular vesicles (sEV)
Cytotoxic T lymphocyte
Warburg’s effect
Online Access:https://doi.org/10.1186/s12935-022-02755-z

Internet

https://doi.org/10.1186/s12935-022-02755-z

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